Tag Archives: bioperine

Saba ACE

Saba ACE Review

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Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 0.0/5 (0 votes cast)

Saba ACE is a weight management and energy formula that has been developed to provide dieters with the following benefits as they commit to their efforts to lose weight:

  • Fat loss
  • Weight loss
  • Appetite control
  • Energy
  • Relief from fatigue
  • Mood improvement
  • Focus improvement

If this OTC diet pill manages to provide all these benefits, it could certainly help make it easier for a dieter to stick to a calorie-controlled eating plan and engage in regular exercise. Naturally, the only way to know how well it can deliver on these benefits is to have a look at its ingredients list.

Saba ACE Formula

When this Saba ACE review was created, there were a number of ingredients within the formula. These included:

  • Vitamin B6
  • Vitamin B12
  • Chromium

Saba ACE Proprietary Blend

  • Caffeine Anhydrous
  • GreenSelect Phytosome
  • Irvingia Gabonensis
  • Garcinia Cambogia
  • Dynamine
  • Apple Cider Vinegar
  • L-Theanine
  • Evodiamine
  • BioPerine

The ingredient that the manufacturer touts the most for Saba ACE is GreenSelect Phytosome. This is a proprietary lecithin formulation of a caffeine-free green tea catechin extract. There have been some studies conducted on this ingredient and findings have been promising in showing that GreenSelect Phytosome has clinical potential for the maintenance of weight after intentional weight loss. That said, keep in mind that simply because an ingredient shows potential this doesn’t mean that it’s proven. Additionally, remember that while this ingredient may have been studied, it has not been studied as part of the Saba ACE formula.

It should also be noted that in addition to the makers of Saba ACE claiming that GreenSelect Phytosome is clinically proven, it also states that irvingia gabonensis (African Mango) is clinically proven, which it is not.

An Energy Boost is Likely and So Is the Risk of Side Effects

Based on the Saba ACE ingredients list, it appears that this diet pill is likely to provide an energy boost, increase mental alertness and support enhanced metabolism. The simple reason being that it contains the stimulant caffeine.

Although it is not revealed how much caffeine is present in 1 serving size (1 capsule), as the caffeine is part of a blend, it is likely to be a notable amount. This is believed for two reasons. The first is that it is the first ingredient listed in the blend. The second is that the suggested use instructions warn users not to take a dose near bedtime as it could cause restlessness. As such, there is likely enough caffeine in this product that those who are sensitive to stimulants should probably think twice before taking it.

The bottom line is that there is no solid proof that Saba ACE is a quality and safe dietary supplement for weight management, especially when the manufacturer makes false claims about proven ingredients.


system-six diet pills

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Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 3.6/5 (3 votes cast)

System-Six is a non-prescription diet supplement manufactured and sold by Irwin Naturals.  For a long time, it had been widely available in terms of mention online, but that was quite difficult to purchase.  At the time, it did not have a presence or mention on the official website of its manufacturer.

System-Six Online

Since then, Irwin Naturals has added System-Six to its website, featuring it on a page of its own. On that page, the product description promises dieters that use this supplement that they will benefit from:

  • Thermogenesis
  • Energy
  • Mood
  • Metabolism
  • Carbohydrate support
  • Antioxidants

Higher Cost than the Price Tag Suggests

Upon reading the marketing materials for System-Six, it doesn’t seem to offer much in terms of unique benefits when compared to other diet pills.  At first glance, it would appear the product is extremely inexpensive on the official website, at $16.99 for a bottle of 60 pills. However, upon reading the product label, it becomes clear that 60 pills won’t last very long.

The usage directions indicate that users should take 3 liquid soft gels at a time with a meal and a full glass of water.  The first set of pills should be taken in the morning and the second set of pills should be taken in the afternoon. This means that when taken at this rate, the full bottle will last only ten days.  It would take three days to provide a full 30-day supply of the product, making the price of using it a much higher $50.97.

Changing Diet Pill Ingredients

Upon the initial writing of this review, the System-Six ingredients were listed as St. John’s Wort Extract, Advantra-Z Citrus Aurantium Extract, Guarana, Yerba Mate, 5-HTP, Betaine, Chromium Picolinate, Garcinia Cambogia, Cayenne, Ginger Root, L-Carnitine, L-Tyrosine, Green Tea Extract, Spirulina, Kola Nut Extract and Bioperine.

However, as of June 2020, the ingredients are now listed as an exceptionally long:

  • Vitamin C
  • Vitamin E
  • Thiamin
  • Riboflavin
  • Niacin
  • Vitamin B12
  • Pantothenic acid
  • Choline
  • Selenium
  • Chromium
  • Fish oil
  • Garcinia
  • White tea extract
  • Green tea extract
  • Avantra Z Bitter Orange extract
  • L-Carnitine
  • Schisandra
  • L-Theanine
  • L-Tyrosine
  • Inositol
  • Cayenne powder
  • Ginger powder
  • Guarana
  • Yerba mate
  • Spirulina powder
  • Bioperine Complex (black pepper extract, ginger extract)

System-Six diet pills contain a few ingredients that are known to aid weight loss. For example, citrus aurantium, guarana, yerba mate, garcinia cambogia and green tea extract are all used to enhance metabolism, which is beneficial when you are trying to lose weight. These ingredients are very common in other non-prescription diet pills.  That said, it’s important to note that this provides a high dose of stimulants which may lead to side effects or health interactions with certain users.

Can System-Six Support Your Diet?

Overall, System-Six diet pills may be beneficial in increasing your energy levels and may help to boost your alertness and focus, however verifiable positive customer reviews and reputable research are hard to come by. Moreover, one of the major drawbacks of taking these diet pills is the sheer number you need to take, requiring many bottles to be purchased to keep up with ongoing use.

Thermo-Cuts Extreme

Thermo-Cuts Extreme Reviews

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Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 1.0/5 (1 vote cast)

Thermo-Cuts Extreme is the stronger version of the Optimum Nutrition dietary supplement called Thermo Cuts. This nonprescription diet pill has a very similar (long) list of ingredients to its cousin, but also includes hydroxycitric acid (HCA) as an ingredient.

Not only are many reviewers already claiming that this product is simply another ineffective OTC diet pill, but it is also being compared to other supplements containing HCA which are being suspected of causing the side effects that have led the FDA to speak out against several different dietary supplements for weight loss.

FDA Warns About Using Certain Products

In May of 2009, the FDA released a statement that recommended that all users of Hydroxycut diet products should stop using them right away as they have a risk of liver-related side effects  that can be anywhere from mild to life-threatening.

Though Thermo-Cuts Extreme is not made by Hydroxycut (which recalled every one of their products), it does include the ingredient HCA which is suspected to be the culprit behind the many undesirable side effects that had been seen in the Hydroxycut products. These side effects include:

  • Jaundice
  • Light colored stools
  • Brown urine
  • Itching
  • Weakness
  • Stomach pain
  • Vomiting
  • Loss of appetite
  • Unusual fatigue
  • Other liver-related issues

Thermo-Cuts Extreme Ingredients

The Thermo-Cuts Extreme formula includes:

  • Chromium – An ingredient with conflicting clinical trial results
  • Garcinia Cambogia Extract – The source of the HCA
  • NeOptuna Extract
  • Caffeine Anhydrous – A fancy word for caffeine, a stimulant which can boost energy, though it does often lead to stimulant-related side effects such as sleeplessness, headaches, and jitters
  • Phase 2 Brand White Kidney Bean Extract – Can help with weight loss, but only in high concentrations, which is unlikely within the Thermo-Cuts Extreme formula
  • Green Tea Extract – Has the potential to be effective in very high doses that are unlikely within this pill
  • Promilin
  • Conjugated Linoleic Acid – CLA can contribute to weight loss when taken in high doses, but not in the lower doses of Thermo-Cuts Extreme
  • Grapefruit Peel Extract
  • Bioperine – Helps the body to absorb nutrients from food but has never been shown to help with weight loss
  • Vanadyl Sulfate

Other Things to Consider

Though it may look like an inexpensive product at $25.99 (at the time this Thermo-Cuts Extreme review was written) per 200 capsules, since you are required to take as many as 12 of those capsules every day, a single bottle will last only 16 days, requiring two bottles (and 400 capsules!) per month. This is neither inexpensive nor realistic considering that the ingredients do not show promise for being very effective at assisting with weight loss.

The bottom line is that due to a lack of evidence about the safety and efficacy of these ingredients and the fact that it contains HCA, it would probably best to avoid taking Thermo-Cuts Extreme.

Thermo-Cuts Extreme Update – June 2020

Thermo-Cuts Extreme is no longer available for purchase. Optimum Nutrition is still in existence and continues to sell weight management aids. However, Thermo-Cuts Extreme is not a part of the products it sells. This is most certainly for the better considering the formula contained a number of unproven ingredients as well as far too many in order for them to have the potential to be beneficial to the user.

Avoid Diet Pills with Too Many Ingredients

It is important to check out the ingredients in any diet pill formula you are considering purchasing and (more importantly) ingesting. It is not only imperative to make sure you are not allergic to any of the substances, but also to investigate the quantities of these substances and what potential benefits these ingredients can provide based on clinical research that has been conducted on them.

As a general rule, it’s typically best to avoid products like Thermo-Cuts Extreme that have a long list of ingredients (inside or outside of a blend). The reason isn’t only because this could mean the potential for a wider range of unwanted side effects, but also because, typically, the more ingredients a formula has, the less likely they are to offer you any real benefits as there won’t be enough of each ingredient included in the formula for it to make any difference to your weight loss efforts. It’s far better to spend your money on products that are actually worth your time.


zalestra reviews

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Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 4.0/5 (1 vote cast)

The Zalestra weight loss supplement by the manufacturer Optimal Therapeutics has taken the unique niche marketing strategy of gearing itself toward pre-menopausal and menopausal women who are struggling with their weight due to the changes in their bodies at this time in their lives.

Marketing materials for this product stress its unique design to help the specific needs of these women who need to support the balance of their hormones and “naturally” lose weight. It even claims that women taking Zalestra will experience fewer menopausal symptoms and a decrease in those they do experience such as:

  • Hot flashes
  • Reduced energy levels
  • Mood swings

A Look at the Zalestra Ingredients

The ingredients of Zalestra are fully listed on the website, which is promising, though the quantities of each ingredient are not listed so it is hard to tell whether or not there is enough of any given ingredient to make it effective.

That being said, the list in itself is a step above some drugs on the market. These ingredients include:

  • Green Tea Extract
  • Guggul Extract
  • Octopalean
  • Maca Root Powder
  • Jojoba Meal Extract
  • Indole-3-Carbole
  • Borage Oil Powder
  • Mega Soy Extract
  • Manganese
  • Black Cohosh
  • DHEA
  • Vitex Fruit Extract and Bioperine

Zalestra is far from cheap, being $49.95 per bottle of ninety capsules, but there is some reassurance through an offer from the manufacturer for a thirty-day money-back guarantee for the price of the product (though not the shipping and handling).

Beware Black Cohosh

Among the ingredients, some are quite common in weight loss supplements, such as green tea extract, but it is clear that they have made an effort to gear things toward menopausal women, with the use of black cohosh and maca root powder.

That being said, those are very potent herbs and could be dangerous to some people even in tiny quantities. For example, it is often cautioned that black cohosh should not be used by anyone who has ever had cancer in their lifetimes.

Still, some studies have not found evidence that supports an association between black cohosh and an increased risk of breast cancer. The belief is that it may increase the risk of this form of cancer due to its purposed estrogenic activity. However, further research is required to determine the effects of this herb.

Regardless of beliefs and a few clinical study findings, it is exceptionally important that you discuss this supplement with your doctor before beginning its use.

In this vein, it is also important to note that there are some nutritionists and diet experts that are now under the impression that soy can disrupt hormonal balances instead of balancing it. Nevertheless, the soy ingredient in this drug may not have the intended results at all.

Talk to Your Doctor

The bottom line is that Zalestra’s manufacturer does not provide evidence of any reputable human studies so there is no clinical evidence that its efficacy has been proven for weight loss or the easing of menopausal symptoms.

Without any studies to backup claims, everything this manufacture says about this diet pill is unsubstantiated and is an indication of the company’s lack of integrity. As such, it would likely be in your best interest to avoid taking this product altogether.

Update – May 2020

Zalestra is not available for purchase online as of May 2020. It seems as though this product has been unavailable for some time. Even on Amazon it is listed as “currently unavailable.”

Consult with Your Healthcare Provider

If you are a women who is seeking help with weight loss and who is also looking for a way to relieve menopausal symptoms, it would be in your best interest not to blindly trust the claims of a manufacturer of a dietary supplement, especially without any scientific evidence to backup the claims.

For optimal help in combating unpleasant menopause symptoms and ensuring healthy and safe, long-term weight loss, consult with your healthcare professional about your options. They can help you find the diet, exercise and behavioral habits that can support your weight loss goals while also helping you to best manage your menopause symptoms. You deserve better than buying into shady products like Zalestra, which uses questionable ingredients that have the potential to be unsafe.


360 Lean review

360 Lean

360 Lean review

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Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 0.0/5 (0 votes cast)

360 Lean is a nonprescription weight loss pill that is marketed as a thermogenic, which means that it is a type of fat burner that works by increasing the body temperature to the point that it requires additional calories or fats to be used as fuel. Therefore, the idea behind these pills is that they will make the body warmer so that more of the calories from consumed will be burned off to produce that heat, theoretically making it easier to lose weight.

While there are many pills that make similar claims to those made by 360 Lean, what helps this one to stand out is that there are a lot of positive customer reviews in terms of its effectiveness. That said, customer reviews should be considered to be helpful when making a decision about a product but should not be the only factor that is taken into consideration.

This is also important, because with a bit of a closer look, it is easy to see that while there are many people who like the weight loss that they experience through the use of these pills, there are many people – including those who lost weight – who have experienced powerful side effects that they found to be very uncomfortable and that has stopped many of them from being able to continue forward with this product.

360 Lean is a capsule pill that is made by a company called 360Cut. That company is based in the United States and sells a number of different types of supplement for dieters and bodybuilders. They say that they are “passionate about performance” and have focused many of their products on boosting physical performance as well as to improve some of the functions of the body such as fat burning and even the sleep cycle.

The ingredients that 360Cut chose to include in the 360 Lean formula include: glucuronolactone, sulbutiamine, caffeine, theobromine, white willow bark extract, 7-Keto DHEA, cayenne pepper, bioperine, yohimbine, and toothed clubmoss herb extract. This was the list that was available on the company’s official website at the time of the writing of this review.

It is clear that this product is based primarily on stimulants, but also on cayenne pepper, which contains capsaicin, which does, indeed raise the body temperature. Unfortunately, what has not been scientifically proven about any of those ingredients is whether or not the effect is powerful enough to actually produce measurable weight loss, or if the response exists, but not enough to burn the calories needed to lose weight faster.

Lean Xtreme reviews

Lean Xtreme

Lean Xtreme reviews

VN:F [1.9.20_1166]
Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 0.0/5 (0 votes cast)

Lean Xtreme is a weight loss supplement manufactured by a company called Driven Sports. It is an over the counter pill that has been designed to function as a fat burner. That said, according to the official manufacturer’s website, it has been created to accomplish that goal without using any stimulants within the formulation.

This is an important point for many dieters. Stimulants are commonly used in diet pills because they can potentially provide a range of different benefits from fat burning to appetite suppression, as well as alertness and energy, depending on which ones are used and how much are included in a given formula. However, stimulants can also lead to unwanted side effects when they are used in large quantities or when they are taken by people who have sensitivities to that type of substance.

Aside from being able to provide fat burning without stimulants, Driven Sports also claims that Lean Xtreme will help the body to be able to maintain lean muscle, so that washboard abs will become visible once the fat has been burned away and is, therefore, no longer covering them up. Additionally, these supplements are also supposed to reduce cortisol levels in the body. Cortisol is often nicknamed the “stress hormone” and is often blamed for causing people to gain weight and stopping people from being able to lose it as easily. By reducing the level of cortisol, the idea is that it will make weight loss naturally easier for the user.

Lean Xtreme is marketed to two groups of people. While it is a weight loss supplement, it has also been marketed as a sports product for bodybuilders and other individuals who want to be able to reduce the layer of fat that is covering up their muscles. The idea is to provide more definition to the muscles.

All of those promises sound very appealing, but of course, they are only as good as the benefits that they can actually produce. Therefore, if you are considering the use of Lean Xtreme, then it is recommended that you take two primary steps. The first is to consult with a doctor about the way in which you intend to use this product, and the second is to have a closer look at the ingredients that make up the formula, to ensure that these substances are well known for actually producing the effects that are claimed, without dangerous or unwanted side effects.

At the time that this review was written, the ingredients listed on the official webpage for this product were: green tea extract, salvia miltiorrhiza extract, coleus forskohlii extract, phosphatidylserine, 7b-hydroxy, 17b-dihydro DHEA, and BioPerine.

Metabosyn review


Metabosyn review

VN:F [1.9.20_1166]
Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 0.0/5 (0 votes cast)

Metabosyn is a type of diet pill that is designed to help people to be able to lose weight. The company behind this product is NutriPharm, LLC, which is a large manufacturer of supplements within this category and that is based in Salt Lake City, Utah. That particular location is known to be a hub for very low quality health and weight loss category supplements. That said, just because this product is made in a certain city, it doesn’t necessarily mean that it will not work. It is important to give these diet pills a fair examination before discounting them, altogether.

To start, the company, itself, has had many different customer complaints registered against it, online. However, those complaints appear to be focused primarily on products other than Metabosyn, so there is still a chance that this could be the diamond in the rough.

The product is manufactured in the United States and it can be purchased exclusively within that country. The official website for the product does not offer international shipping options. At the time that this review was written, each bottle contained a month’s supply of the product and it cost $69.95, in addition to the $4.95 domestic shipping fee.

The ingredients that make up the Metabosyn formula were listed as being: green coffee bean extract, Chromax, raspberry ketone, lipolide SC, phenyethylamine, caffeine anhydrous, evodiamine, humulus lupulus, methyl synephrine, ginger root, quercetin, vitamin B12, and bioperine.

There are a few concerns that should start to rise when looking at this list of ingredients. The first is that this is a relatively long list, so it is hard to tell whether or not it is possible for enough of the ingredients to be used to produce any benefit – if there is any to be had. However, the second problem is that there is a potentially dangerous combination within this list. That combination is between the methyl synephrine and the caffeine anhydrous.

Caffeine anhydrous, on its own, is usually considered to be a well tolerated stimulant that is safe to use for most dieters on a regular basis. In fact, it has been extensively researched and it has been connected with a number of weight loss supporting benefits such as a metabolic boost, increased alertness, and even appetite suppression for some people.

On the other hand, synephrine is an ingredient that has been associated with some potentially dangerous side effects, to the point that the FDA has warned dieters not to use supplements that contain that ingredient. Furthermore, a growing body of research has shown that when synephrine is combined with other stimulants, especially caffeine, the risk of those dangerous side effects – such as stroke or heart attack – climbs significantly.

Lipo 13 review

Lipo 13

Lipo 13 review

VN:F [1.9.20_1166]
Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 0.0/5 (0 votes cast)

Lipo 13 is an over the counter supplement that has been designed to help dieters to be able to achieve faster and easier weight loss. It is manufactured by Ecopharma, which is a company that is headquartered in Belgium. Originally, this product was sold under the label “Lipo XR”, but Ecopharma has now changed the name of these diet pills, and the ingredients have been slightly changed within the formula from what they had been under the old brand name.

According to the manufacturer, each of the ingredients within the formula for Lipo 13 has been clinically tested. That said, while it did say that testing occurred, it did not actually reveal the results of those tests on the website. This leaves the visitor to assume that the results were positive in terms of effectiveness and safety, though it never specifically says this. This could be a matter of either sloppy or careful wording on the website, neither of which reflects very well on the product.

This impression is made worse by the fact that Lipo XR had been sold with a 14 day money back guarantee. This may be a very short guarantee, but at least it was there. At the time of this review, no mention of that guarantee could be found on the official website.

To gain a better understanding of Lipo 13, it is a good idea to examine the formula for this product, which claims to be clinically tested. The ingredients listed on the official website at the time of this review are: citrin HCA, green tea, forslean, guarana, yerba mate, bioperine, L-carnitine, choline bitartrate, magnesium, L-tyrosine, zinc, vitamin B6, and chromium.

This list makes it very clear that while these ingredients may have been clinically tested, they are not proven and that the wording on the website was strategic and not careless. This problem could be identified with the chromium, alone. The Mayo Clinic, a highly reputable medical organization, has included chromium among the ingredients that it has labeled inadequately studied when it comes to the claims being made for use in a diet pill.

Moreover, it is clear that this formula is highly based on powerful stimulants. The citrin HCA, green tea, guarana, and yerba mate are examples of powerful stimulants on their own, but even more powerful when combined. This may seem appealing because stimulants are known for helping to reduce the appetite and boost energy levels and fat burning, except that when they are combined to a very powerful degree, then any benefits may be negated by the risk of unwanted and unpleasant side effects such as sleeplessness, jitters, anxiety, headaches, and more.

Pyro MX Leancore review

Pyro MX Leancore

Pyro MX Leancore review

VN:F [1.9.20_1166]
Weight Loss Effects
Suppresses Appetite
Increases Energy
Value for Money
Rating: 0.0/5 (0 votes cast)

Pyro MX Leancore was developed by a company called Sci-MX, which is based in the United Kingdom and is somewhat new when compared to many other players within the nonprescription weight loss market. These diet pills are meant to provide dieters with fat oxidation and metabolism boosting when they have been taken multiple times every day. The official web page for the product, on the manufacturer’s website, says that users can expect to see results within a short span of time.

Before taking this Pyro MX Leancore, it is very important to learn about its ingredients and to discuss it with a doctor. Fortunately, the official webpage does offer consumers a full list of all of the ingredients that make up the formula, as well as the quantities of every substance. This is a positive sign when it comes to diet pills.

Within this Pyro MX Leancore, a dieter will be taking the Pyro-Therm complex, which is made up of a total of 184 mg of caffeine per serving (three capsules) from guarana, bitter orange peel, yerba mate, and cayenne pepper. They will also be taking green tea extract (which also contains caffeine above and beyond that amount), acetyl carnitine, white kidney bean extract, tyrosine, Bioperine ®, vitamin B5 and chromium.

Immediately, it should stand out to many people who are familiar with this industry that the product is contains a very high amount of stimulants. While some stimulants, used within reason, can produce an effect that not only boosts the metabolism but that also helps to reduce the size of the appetite, they are notorious for causing unwanted side effects among some users. These can include anything from headaches and jitters, to anxiety, nausea, sleeplessness, and other uncomfortable problems. These do not necessarily occur in everyone who uses stimulants, but they are not uncommon.

The second issue that is rather worrisome is that this product contains bitter orange. This is a very powerful stimulant which will boost the overall stimulation and risk of side effects, but this individual ingredient stands out from among the others because it comes with a warning from the FDA. The U.S. Food and Drug Administration has released a caution to consumers who buy diet pills online or in stores with regards to this substance because it contains synephrine. Synephrine is a very powerful stimulant that became popular when ephedra was banned, back in the 1990s. It has been associated with strong side effects that can be dangerous for some people, such as spiking blood pressure, convulsions, and others.